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Antiviral Agents
11 articles analyzed — Average score : 47/100
Grade distribution
Authors' conclusions
Articles
B
Mostly reliable (73/100)
Effect of Hydroxychloroquine in Hospitalized Patients with Covid-19. Negative
Horby P et al.·The New England journal of medicine·Oct 2020
B
Mostly reliable (71/100)
Remdesivir for the Treatment of Covid-19 - Final Report. Positive
Beigel JH et al.·The New England journal of medicine·Oct 2020
B
Mostly reliable (68/100)
Baricitinib plus Remdesivir for Hospitalized Adults with Covid-19. Positive
Kalil AC et al.·The New England journal of medicine·Mar 2021
B
Mostly reliable (62/100)
Hydroxychloroquine with or without Azithromycin in Mild-to-Moderate Covid-19. Negative
Cavalcanti AB et al.·The New England journal of medicine·Jul 2020
B
Mostly reliable (60/100)
A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19. Negative
Cao B et al.·The New England journal of medicine·Mar 2020
B
Mostly reliable (56/100)
Molnupiravir for Oral Treatment of Covid-19 in Nonhospitalized Patients. Positive
Jayk Bernal A et al.·New England Journal of Medicine·Mar 2022
C
Nuanced (55/100)
Oral Nirmatrelvir for High-Risk, Nonhospitalized Adults with Covid-19. Positive
Hammond J et al.·New England Journal of Medicine·Apr 2022
C
Nuanced (51/100)
Phase 2b trial of interferon-free therapy for hepatitis C virus genotype 1. Positive
Kowdley KV et al.·The New England Journal of Medicine·Jan 2014
E
Not reliable (25/100)
Ivermectin for Prevention and Treatment of COVID-19 Infection: A Systematic Review, Meta-analysis, and Trial Sequential Analysis to Inform Clinical Guidelines. Positive
Bryant A et al.·American Journal of Therapeutics·Jun 2021
X
Invalidated (0/100)
Retracted
Cardiovascular Disease, Drug Therapy, and Mortality in Covid-19. Negative
Mehra MR et al.·The New England Journal of Medicine·May 2020
X
Invalidated (0/100)
Retracted
RETRACTED: Hydroxychloroquine or chloroquine with or without a macrolide for treatment of COVID-19: a multinational registry analysis. Positive
Mehra MR et al.·The Lancet·May 2020